CASCAIS, PORTUGAL: The ISTH is hosting its Second Annual Advanced Training Course on Thrombosis and Haemostasis on March 13-16, 2014, at the Hotel Quinta da Marinha in Cascais, Portugal. As part of the Society’s mission, the course will provide the latest training in the treatment of thrombosis and bleeding disorder management to meet the needs of hematologists and related specialists around the world. Space is limited to only 200 participants; early registration is recommended to ensure availability.
The meeting will provide three full days of intense examination on the subjects of blood coagulation and bleeding disorders, platelets and venous thrombosis. Leading scientists with vast experience in education will deliver focused lectures followed by ample time for discussion and close interaction with the participants. Meet the Expert sessions will be devoted to discussion groups with the day’s speakers. There will also be interactive sessions in the evening with exercises relating to the analysis of the topics discussed during the day or on clinical case studies. A formal program is available here.
The second EHA-SWG Scientific Meeting, titled Focus on Thrombocytopenia & platelet function disorders took place in Lisbon, Portugal, from September 27-29, 2013.
The meeting was chaired by Roberto Stasi, MD from the Heamtology Unit from St. George`s Hospital, London, UK.
101 participants attended the meeting from Europe, Middle-East, Australia and United States. Attendance included faculty members, trained and in training doctors involved in the field of platelet disorders.
Hematology is one of few medical disciplines that have made significant steps in realizing the promise of personalized medicine. Together with ESMO and Eurocan Platform and in the context of our membership of the European Alliance for Personalised Medicine (EAPM), EHA was involved in the organization of a Roundtable ‘Oncology/Haematology: How to provide the right prevention and treatment to the right patient at the right time’.
Transfusion of erythrocytes is the most common form of cellular therapy. It rapidly restores the oxygen supply to the tissues in patients suffering from sudden blood loss, reduced erythrocyte production following for instance cytotoxic cancer treatment, or in patients suffering from chronic anemia due to congenital diseases such as sickle cell disease and thalassemia. Matching transfusions for ABO and Rh-D blood group antigens is in general sufficient for successful transfusion. However, over 300 additional blood group antigens are known, against which we do not normally generate antibodies, and that are not matched for in general transfusion practice.
Stockholm, June 14, 2013 Dr Wyndham Wilson will give an update on recent developments in the treatment of lymphomas with small molecules. The last 30 years have seen a plethora of treatments for diffuse large B-cell lymphoma (DLBCL) but few advances have been made. Recent studies have identified B-cell receptor signaling as critical for many B-cell lymphomas including the most common type, called diffuse large B-cell lymphoma (DLBCL). Recent studies have shown that DLBCL is actually not a single disease but at least 3 different diseases, each with its own critical abnormalities that allow it to survive as a malignancy. The most difficult to treat type of DLBCL is called the Activated B-cell (ABC) subtype, which is dependent on abnormal signaling of the B-cell receptor (BCR). Work by Dr. Lou Staudt has shown that these tumors will die when this pathway is inhibited.
Stockholm, June 14, 2013 Dr Jesus San-Miguel will present promising results of a phase 3 study in multiple myeloma.
Treatment for patients with multiple myeloma (MM) has improved over the last decade due to the introduction of new drugs such as lenalidomide and bortezomib. However, after receiving multiple treatments, MM patients often become resistant (refractory) to these drugs and have an average survival of only 9 months.
Stockholm, June 14, 2013 Dr Elizabeta Nemeth will present findings of a study in patients with iron overload disorders that will contribute to the design of a potential new treatment at the 18th Congress of the European Hematology Association in Stockholm.
Stockholm, June 14, 2013 Dr Ross Levine will present the results from a study on targeting the JAK-STAT pathway in myeloproliferative neoplasms.
Stockholm, June 14, 2013 Dr Valentin Goede will present promising outcomes for elderly CLL patients at the 18th Congress of the European Hematology Association in Stockholm.
Hematopoietic stem cells (HSCs) regenerate blood cells throughout the lifespan of an individual. The HSC pool has to accommodate to the cellular stresses associated with its life-long activity. HSCs are protected in specific bone marrow areas called “niches”. New technologies allow the analysis of different bone marrow compartments and the functional implications on HSCs. HSCs persist for a lifetime; there is a balance between their proliferation and their quiescent (sleeping) state. Therefore, the HSCs cell cycle is controlled by factors within and outside the cell.